EGCG (Epigallocatechin gallate) is a type of catechin and a flavonoid that can be found in green tea. Green tea is produced from a plant called Camellia sinensis and is the second most consumed beverage in the world (only behind water). It has been widely studied first as a cancer prevention substance and more lately as an anti-cancer agent.
Its mechanism of action is not completely understood as of yet, but it seems to be a potent regulator of many different metabolic pathways inside cells, being capable of affecting both cell proliferation and inducing apoptosis in selected cell types. EGCG seems to be also capable of disrupting angiogenesis – the disorganized building of new blood vessels by malignant tumors.
EGCG can interfere in many different metabolic pathways which are common for many different cancer types, so it may be used in a number of different diseases, like breast, cervical and lung cancers for example. Outside of the alternative oncology, it has been used as an anti-inflammatory and anti-oxidative drug.
We believe that EGCG may have great value in cancer therapy when coupled with other treatment modalities and may be used for a number of different types of cancer. We only recommend the intravenous use of EGCG when regarding its anti-neoplastic usage because we feel that the oral intake is not enough to reach the required amounts of the drug in the bloodstream. This treatment is usually well tolerated by patients, that only experience little to no side effects.