5-Fluorouracil is a chemotherapy drug that was patented in 1956. It is used to treat different cancers including colon, breast, skin, stomach, oesophageal (gullet), and pancreatic cancer. It may also be used to treat other cancers.
The drug is usually given by injection into a vein. Topical (on the skin) forms are available too. Basal cell carcinoma and skin warts are some of the indications for the creme.
5-Fluorouracil is classified as an “antimetabolite” and blocks certain enzymes of the DNA. As a result, tumor growth is slowed down.
Folinic acid, also known as leucovorin, is used in combination with 5-fluorouracil to enhance its effect. When given in combination the side effects of 5-Fluorouracil may be more severe.
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<a href='https://dr-adem.com/increase-efficacy-of-5-fluorouracil/'><img src='https://dr-adem.com/wp-content/uploads/2019/10/5-Fluorouracil-how-to-improve-the-efficacy.jpg' alt='Increase Efficacy Of 5-Fluorouracil'/></a>Common side effects are:
- Diarrhea
- dry and itchy skin, skin darkening
- Nausea, vomiting, and loss of appetite
- Mouth sores
- Hair loss
- Low blood counts
Drug interactions may increase your risk of serious side effects. Inform your doctor about all the products you use. It is known that certain antibiotics like metronidazole and blood thinner like warfarin are interacting with 5-Fluorouracil.