Shogaol is a group of compounds naturally found in ginger and which give it its spicy feature. It has been used in Chinese traditional medicine for a long time to treat diabetes, cardiovascular diseases, and rheumatism. In the last years, it has been studied as a possible antibacterial drug. Specifically, 6-Shogaol has shown promise in the fight against cancer as an anti-oxidant, anti-inflammatory, and antitumor drug.
Shogaol seems to affect cancer cells in a number of different ways. It has the capability of decreasing the amount of glucose that goes into cancer cells (which need large quantities of glucose due to its accelerated metabolism) as well as modulating some tumor-related immunologic pathways (like mTOR receptors). Through such mechanisms, Shogaol could have an important role in anti-neoplastic therapy.
As all cancer cells need glucose to thrive (regardless of which type of cancer), Shogaol could be used by almost all cancer patients. It has shown more promise in treating breast, fibrosarcoma, prostate, and gastrointestinal tract cancers. Outside of the alternative oncology, Shogaol has shown also some effectiveness against diabetes and cardiovascular diseases.
We believe that Shogaol may be used in a number of different cancer types (e.g. colon cancer) as part of a more comprehensive anti-cancer strategy. We recommend only the intravenous use of the drug when used as an anti-neoplastic agent. Furthermore, Shogaol hasn’t been related to any major side effects, so patients usually tolerate it well. It is not suited as a single-agent therapy and oral intake is not enough to reach the required levels in the bloodstream.